OBJECTIVE:To investigate the LRP expression in acute leukemia and the relationship between the expression and clinical remission rate.METHODS:The levels of LRP were detected by monoclonal antibodies and flow cytometry in 15 normal controls a[...]
Expression and clinical significance of lung resistance-related protein in acute leukemia
Posted by Cancer Research on 04-14-2012
Posted in Leukemia 
Tags: leukemia/drug therapy,acute disease,neoplasm proteins/biesynthesis,flow cytometry,
Expression of Survivin Gene in NB4 Cell Line and Cells of Acute Promyelocytic Leukemia and Its Anti-apoptosis and Clinical Significance
Posted by Cancer Research on 04-14-2012
The study was aimed to detect expression rate of survivin gene in APL cell and to explore the relationship between its expression and clinical manifestation. PML/RARα and survivin mRNA expression were analyzed by using reverse transcriptase[...]
Posted in Leukemia Tags: cell strains,NB4,survivin,PML/RAR_α fusion gene,acute promyelocytic leukemia,
Value of PET/CT with ~(18)F-FDG in the diagnosis of lung cancer
Posted by Cancer Research on 04-14-2012
To investigate the value of PET / CT with 18F-FDG in the diagnosis of lung cancer. Methods:A retrospective analysis was performed on 168 patients with pulmonary lesions (115 malignant,53 benign) by 18F-FDG PET / CT from October 2006 to Janua[...]
Comparison of pemetrexed and docetaxel as single chemotherapy in advanced non-small cell lung cancer
Posted by Cancer Research on 04-14-2012
OBJECTIVE: To compare the efficacy and adverse reactions of pemetrexed and docetaxel in advanced non-small cell lung cancer(NSCLC) previously treated with first-line chemotherapy.METHODS: Totally 84 advanced NSCLC cases,who had failed or not[...]
Posted in Lung Cancer Tags: carcinoma,non-small cell lung/drug therapy,glutamates,paclitaxel,antineoplastic agents,
Application of Metaphase-Fluorescence in Situ Hybridization to the Diagnosis of Acute Promyelocytic Leukemia and the Detection of Minimal Residual Disease
Posted by Cancer Research on 04-14-2012
To investigate the value of metaphase-fluorescence in situ hybridization (M-FISH) in the diagnosis of acute promyelocytic leukemia (APL) and the detection of its minimal residual disease (MRD), 10 cases of untreated acute myeloid leukemia (A[...]
Posted in Leukemia Tags: acute promyelocytic leukemiaminimal residual diseasemetaphase-fluorescence in situ hybridizationcytogeneticsreverse transcription-polymerase chain reaction,
EFFECTS OF NEOADJUVANT CHEMOTHERAPY ON MDR1 AND MRP GENE EXPRESSION IN PRIMARY BREAST CANCER
Posted by Cancer Research on 04-14-2012
To investigate the effects of neoadjuvant chemotherapy on the expression of drug resistance genes, multidrug resistance-1 (MDR1) and multidrug resistance-associated protein (MRP), in patients with primary breast cancer. Methods: MDR1 and MRP[...]
Posted in Breast Cancer Tags: Breast cancer,Neoadjuvant chemotherapy,Drug resistance (MDR1),Multidrug resistance-associated protein (MRP),
Synergistic Effect of the Combination of Toremifene with Gemcitabine on Growth and Apoptosis in Human Lung Cancer Cell Line A549
Posted by Cancer Research on 04-14-2012
To study synergistic effect of toremifene combined with gemcitabine on human lung cancer line A549,and to provide a new clinical approach for lung cancer.Methods Cell proliferation was evaluated by MTT assay.Morphological change of cell apop[...]
Posted in Lung Cancer Tags: Toremifene,Gemcitabine,Chemotherapy,Lung adenocarcinoma cell,Synergistic effect,
Radioimmunotherapy of breast cancer cell lines with ~(131)I-herceptin
Posted by Cancer Research on 04-14-2012
To explore the biologic response of breast cancer cell lines highly expressing Her-2 gene to 131I-herceptin.Methods The inhibitory effect of 131I-herceptin on SK-BR-3,MDA-MB-231 and MCF-7 cell lines expressing different levels of Her-2 gene[...]
